• Akash Anavarathan

San Francisco-Arizona: Cardinals open as 7.5-point favorites at home

The San Francisco 49ers may not be a favorite in any one of their 16 games this week. They're 0-3, but their Week 3 loss against the Los Angeles Rams was a tough one. They may be missing Carlos Hyde (hip) along with Eric Reid and Reuben Foster -- who have already been ruled out.

On the flip side, Arizona comes into this game at 1-2, dropping games against the Cowboys and the Lions. They played tough against the Cowboys, but lost the game down the stretch. Below are the odds for the Arizona-San Francisco matchup.

Spread: San Francisco +7.5

O/U: 44.5 points

Moneyline: San Francisco +269, Arizona -275

The odds are coming from OddsShark and I think San Francisco has a good chance to cover the 7.5 points, even if they don't win the game. I would bet the under and also take Arizona on the moneyline.

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