The Seattle Seahawks have had the 49ers' number ever since the early Harbaugh days. The 49ers haven't won in Seattle since December 2011 and have lost to the Seahawks seven straight times.
The 49ers have overhauled their roster, coaching staff and front office, but their product on the field, still doesn't match up to the level of what Seattle has.
The Seahawks are trying to contend for a Super Bowl, while the 49ers are trying to raise themselves back into relevancy. Their Week 2 matchup will feature both teams looking to find their first win of the season.
Spread: San Francisco +13.5
O/U: 43 points
Moneyline: San Francisco +600, Seattle -750
The odds have been set by OddsShark and I think Seattle will cover the 13.5 points at home. Their offensive line is abysmal, but they still have Russell Wilson, that vaunted defense and the crowd noise fully behind them.
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